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Blocking Complement Factor B Activation Reduces Renal Injury and Inflammation in a Rat Brain Death Model

Introduction: The majority of kidneys used for transplantation are retrieved from brain-dead organ donors. In brain death, the irreversible loss of brain functions results in hemodynamic instability, hormonal changes and immunological activation. Recently, brain death has been shown to cause activat...

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Detalles Bibliográficos
Autores principales: Jager, Neeltina M., van Zanden, Judith E., Subías, Marta, Leuvenink, Henri G. D., Daha, Mohamed R., Rodríguez de Córdoba, Santiago, Poppelaars, Felix, Seelen, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838866/
https://www.ncbi.nlm.nih.gov/pubmed/31736957
http://dx.doi.org/10.3389/fimmu.2019.02528