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Blocking Complement Factor B Activation Reduces Renal Injury and Inflammation in a Rat Brain Death Model
Introduction: The majority of kidneys used for transplantation are retrieved from brain-dead organ donors. In brain death, the irreversible loss of brain functions results in hemodynamic instability, hormonal changes and immunological activation. Recently, brain death has been shown to cause activat...
Autores principales: | Jager, Neeltina M., van Zanden, Judith E., Subías, Marta, Leuvenink, Henri G. D., Daha, Mohamed R., Rodríguez de Córdoba, Santiago, Poppelaars, Felix, Seelen, Marc A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838866/ https://www.ncbi.nlm.nih.gov/pubmed/31736957 http://dx.doi.org/10.3389/fimmu.2019.02528 |
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