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Metformin protects against PM(2.5)-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2

Fine particulate matter (PM(2.5)) airborne pollution increases the risk of respiratory and cardiovascular diseases. Although metformin is a well-known antidiabetic drug, it also confers protection against a series of diseases through the activation of AMP-activated protein kinase (AMPK). However, wh...

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Detalles Bibliográficos
Autores principales: Gao, Junling, Yuan, Juntao, Wang, Qiao'e, Lei, Tong, Shen, Xiyue, Cui, Bingqing, Zhang, Fang, Ding, Wenjun, Lu, Zhongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838896/
https://www.ncbi.nlm.nih.gov/pubmed/31669973
http://dx.doi.org/10.1016/j.redox.2019.101345