Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches

Tumor cells must generate sufficient ATP and biosynthetic precursors in order to maintain cell proliferation requirements. Otto Warburg showed that tumor cells uptake high amounts of glucose producing large volumes of lactate even in the presence of oxygen, this process is known as “Warburg effect o...

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Detalles Bibliográficos
Autores principales: de la Cruz-López, Karen G., Castro-Muñoz, Leonardo Josué, Reyes-Hernández, Diego O., García-Carrancá, Alejandro, Manzo-Merino, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839026/
https://www.ncbi.nlm.nih.gov/pubmed/31737570
http://dx.doi.org/10.3389/fonc.2019.01143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839026/
https://www.ncbi.nlm.nih.gov/pubmed/31737570
http://dx.doi.org/10.3389/fonc.2019.01143

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