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Compound Dynamics and Combinatorial Patterns of Amino Acid Repeats Encode a System of Evolutionary and Developmental Markers

Homopolymeric amino acid repeats (AARs) like polyalanine (polyA) and polyglutamine (polyQ) in some developmental proteins (DPs) regulate certain aspects of organismal morphology and behavior, suggesting an evolutionary role for AARs as developmental “tuning knobs.” It is still unclear, however, whet...

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Detalles Bibliográficos
Autores principales: Pelassa, Ilaria, Cibelli, Marica, Villeri, Veronica, Lilliu, Elena, Vaglietti, Serena, Olocco, Federica, Ghirardi, Mirella, Montarolo, Pier Giorgio, Corà, Davide, Fiumara, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839033/
https://www.ncbi.nlm.nih.gov/pubmed/31589292
http://dx.doi.org/10.1093/gbe/evz216