Targeting of CXCR3 improves anti-myeloma efficacy of adoptively transferred activated natural killer cells

BACKGROUND: The peculiar multiple myeloma microenvironment, characterized by up-regulated levels of several inflammatory chemokines, including the CXCR3 receptor ligands CXCL9 and CXCL10, limits NK cell positioning into the bone marrow by interfering with CXCR4 function. It is still unclear if the c...

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Detalles Bibliográficos
Autores principales: Bonanni, Valentina, Antonangeli, Fabrizio, Santoni, Angela, Bernardini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839099/
https://www.ncbi.nlm.nih.gov/pubmed/31699153
http://dx.doi.org/10.1186/s40425-019-0751-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839099/
https://www.ncbi.nlm.nih.gov/pubmed/31699153
http://dx.doi.org/10.1186/s40425-019-0751-5

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