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Targeting of CXCR3 improves anti-myeloma efficacy of adoptively transferred activated natural killer cells
BACKGROUND: The peculiar multiple myeloma microenvironment, characterized by up-regulated levels of several inflammatory chemokines, including the CXCR3 receptor ligands CXCL9 and CXCL10, limits NK cell positioning into the bone marrow by interfering with CXCR4 function. It is still unclear if the c...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839099/ https://www.ncbi.nlm.nih.gov/pubmed/31699153 http://dx.doi.org/10.1186/s40425-019-0751-5 |