RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation

BACKGROUND: A gap exists in our mechanistic understanding of how genetic and environmental risk factors converge at the molecular level to result in the emergence of autism symptoms. We compared blood-based gene expression signatures in identical twins concordant and discordant for autism spectrum c...

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Detalles Bibliográficos
Autores principales: Saffari, Ayden, Arno, Matt, Nasser, Eric, Ronald, Angelica, Wong, Chloe C. Y., Schalkwyk, Leonard C., Mill, Jonathan, Dudbridge, Frank, Meaburn, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839145/
https://www.ncbi.nlm.nih.gov/pubmed/31719968
http://dx.doi.org/10.1186/s13229-019-0285-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839145/
https://www.ncbi.nlm.nih.gov/pubmed/31719968
http://dx.doi.org/10.1186/s13229-019-0285-1

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