In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligothiophenes (LCOs) enable fluorescence imaging of these protein aggregates. Using LCOs and m...

Descripción completa

Detalles Bibliográficos
Autores principales: Calvo-Rodriguez, Maria, Hou, Steven S., Snyder, Austin C., Dujardin, Simon, Shirani, Hamid, Nilsson, K. Peter R., Bacskai, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839235/
https://www.ncbi.nlm.nih.gov/pubmed/31703739
http://dx.doi.org/10.1186/s40478-019-0832-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839235/
https://www.ncbi.nlm.nih.gov/pubmed/31703739
http://dx.doi.org/10.1186/s40478-019-0832-1

Ejemplares similares