Silencing of TRIM11 suppresses the tumorigenicity of chordoma cells through improving the activity of PHLPP1/AKT

BACKGROUND: Tripartite motif-containing protein 11 (TRIM11), a member of RING family of E3 ubiquitin ligases, is identified as an oncogene in certain human tumors. However, the detailed biological function of TRIM11 in chordoma is still unclear. The purpose of present research is to explore the role...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Wang, Gang, Wang, Qingfeng, Zhu, Ziqiang, Wang, Yunqing, Chen, Kangwu, Yang, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839251/
https://www.ncbi.nlm.nih.gov/pubmed/31719797
http://dx.doi.org/10.1186/s12935-019-1007-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839251/
https://www.ncbi.nlm.nih.gov/pubmed/31719797
http://dx.doi.org/10.1186/s12935-019-1007-7

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