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CDK5RAP3 inhibits angiogenesis in gastric neuroendocrine carcinoma by modulating AKT/HIF-1α/VEGFA signaling

BACKGROUND: Angiogenesis plays critical roles in the progression and metastasis of malignant tumors. Gastric neuroendocrine carcinoma is an uncommon stomach cancer that is rich in blood vessels and exhibits highly malignant biological behavior with a poor prognosis. The role of CDK5RAP3 in GNEC has...

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Detalles Bibliográficos
Autores principales: Lin, Jian-Xian, Weng, Xiong-Feng, Xie, Xin-Sheng, Lian, Ning-Zi, Qiu, Sheng-Liang, Wang, Jia-Bin, Lu, Jun, Chen, Qi-Yue, Cao, Long-Long, Lin, Mi, Tu, Ru-Hong, Yang, Ying-Hong, Liu, Si-Jia, Hu, Min, Lin, Yi-Ke, Huang, Chang-Ming, Zheng, Chao-Hui, Li, Ping, Xie, Jian-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839262/
https://www.ncbi.nlm.nih.gov/pubmed/31728130
http://dx.doi.org/10.1186/s12935-019-0997-5