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Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers

Epigenetic modifications such as histone modification play an important role in tumorigenesis. There are several evidence that histone deacetylases (HDACs) play a key role in cancer induction and progression by histone deacetylation. Besides, histone acetylation is being accessed as a therapeutic ta...

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839273/
https://www.ncbi.nlm.nih.gov/pubmed/31737580
http://dx.doi.org/10.4103/abr.abr_142_19