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Distinct RhoGEFs Activate Apical and Junctional Contractility under Control of G Proteins during Epithelial Morphogenesis

Small RhoGTPases direct cell shape changes and movements during tissue morphogenesis. Their activities are tightly regulated in space and time to specify the desired pattern of actomyosin contractility that supports tissue morphogenesis. This is expected to stem from polarized surface stimuli and fr...

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Detalles Bibliográficos
Autores principales: Garcia De Las Bayonas, Alain, Philippe, Jean-Marc, Lellouch, Annemarie C., Lecuit, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839405/
https://www.ncbi.nlm.nih.gov/pubmed/31522942
http://dx.doi.org/10.1016/j.cub.2019.08.017