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Global Metabolic Shifts in Age and Alzheimer’s Disease Mouse Brains Pivot at NAD(+)/NADH Redox Sites
Age and Alzheimer’s disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation. Yet little is known on how systematic shifts in metabolic networks depend on age and AD. In this work, we investigated the global m...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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IOS Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839468/ https://www.ncbi.nlm.nih.gov/pubmed/31356210 http://dx.doi.org/10.3233/JAD-190408 |