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Global Metabolic Shifts in Age and Alzheimer’s Disease Mouse Brains Pivot at NAD(+)/NADH Redox Sites

Age and Alzheimer’s disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation. Yet little is known on how systematic shifts in metabolic networks depend on age and AD. In this work, we investigated the global m...

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Detalles Bibliográficos
Autores principales: Dong, Yue, Brewer, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839468/
https://www.ncbi.nlm.nih.gov/pubmed/31356210
http://dx.doi.org/10.3233/JAD-190408