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APOE ɛ4 Gene Dose and Sex Effects on Alzheimer’s Disease MRI Biomarkers in Older Adults with Mild Cognitive Impairment

BACKGROUND: APOE ɛ4 and sex have been linked to increased risk for conversion to Alzheimer’s disease (AD). However, the relationship between APOE ɛ4 gene dose, sex, and AD biomarkers remains understudied. OBJECTIVE: To investigate the effect of APOE ɛ4 dose on AD biomarkers in a sample of older adul...

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Detalles Bibliográficos
Autores principales: Hobel, Zachary, Isenberg, A. Lisette, Raghupathy, Dhvani, Mack, Wendy, Pa, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839478/
https://www.ncbi.nlm.nih.gov/pubmed/31424388
http://dx.doi.org/10.3233/JAD-180859