Characterization of Neurodevelopmental Abnormalities in iPSC-Derived Striatal Cultures from Patients with Huntington’s Disease

BACKGROUND: Huntington’s disease (HD) is an inherited neurodegenerative disease and is characterized by atrophy of certain regions of the brain in a progressive manner. HD patients experience behavioral changes and uncontrolled movements which can be primarily attributed to the atrophy of striatal n...

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Detalles Bibliográficos
Autores principales: Mathkar, Pranav P., Suresh, Divya, Dunn, James, Tom, Colton M., Mattis, Virginia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839479/
https://www.ncbi.nlm.nih.gov/pubmed/31381521
http://dx.doi.org/10.3233/JHD-180333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839479/
https://www.ncbi.nlm.nih.gov/pubmed/31381521
http://dx.doi.org/10.3233/JHD-180333

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