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Colocalization of Polycystic Ovary Syndrome Candidate Gene Products in Theca Cells Suggests Novel Signaling Pathways

Genome-wide association studies identified loci associated with polycystic ovary syndrome (PCOS), including those near the LH receptor gene (LHCGR), a clathrin-binding protein (DENND1A) that functions as a guanine nucleotide exchange factor, and the gene encoding RAB5B, a GTPase involved in vesicula...

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Detalles Bibliográficos
Autores principales: Kulkarni, Rewa, Teves, Maria E, Han, Angela X, McAllister, Jan M, Strauss, Jerome F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839531/
https://www.ncbi.nlm.nih.gov/pubmed/31723719
http://dx.doi.org/10.1210/js.2019-00169