Cargando…

Colocalization of Polycystic Ovary Syndrome Candidate Gene Products in Theca Cells Suggests Novel Signaling Pathways

Genome-wide association studies identified loci associated with polycystic ovary syndrome (PCOS), including those near the LH receptor gene (LHCGR), a clathrin-binding protein (DENND1A) that functions as a guanine nucleotide exchange factor, and the gene encoding RAB5B, a GTPase involved in vesicula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kulkarni, Rewa, Teves, Maria E, Han, Angela X, McAllister, Jan M, Strauss, Jerome F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839531/ https://www.ncbi.nlm.nih.gov/pubmed/31723719 http://dx.doi.org/10.1210/js.2019-00169

Ejemplares similares

The PCOS GWAS Candidate Gene ZNF217 Influences Theca Cell Expression of DENND1A.V2, CYP17A1, and Androgen Production
por: Waterbury, Jamaia S, et al.
Publicado: (2022)

Cholesterol Side-Chain Cleavage Gene Expression in Theca Cells: Augmented Transcriptional Regulation and mRNA Stability in Polycystic Ovary Syndrome
por: Wickenheisser, Jessica K., et al.
Publicado: (2012)

Human DENND1A.V2 Drives Cyp17a1 Expression and Androgen Production in Mouse Ovaries and Adrenals
por: Teves, Maria E., et al.
Publicado: (2020)

Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome
por: Harris, R. Alan, et al.
Publicado: (2023)

The Cebpd (C/EBPδ) Gene Is Induced by Luteinizing Hormones in Ovarian Theca and Interstitial Cells But Is Not Essential for Mouse Ovary Function
por: Huang, A-Mei, et al.
Publicado: (2007)

Effects of IL‐18 on the proliferation and steroidogenesis of bovine theca cells: Possible roles in the pathogenesis of polycystic ovary syndrome
por: Zhang, Hong yuan, et al.
Publicado: (2020)

Endocrine Disrupting Chemicals in Polycystic Ovary Syndrome: The Relevant Role of the Theca and Granulosa Cells in the Pathogenesis of the Ovarian Dysfunction
por: Jozkowiak, Malgorzata, et al.
Publicado: (2022)

Colocalization analysis of polycystic ovary syndrome to identify potential disease-mediating genes and proteins
por: Censin, Jenny C., et al.
Publicado: (2021)

Cancer of rat ovaries: Sertoli cell or granulosa-theca cell tumours?
por: Knowles, J. F.
Publicado: (1983)

A new evidence‐based guideline for assessment and management of polycystic ovary syndrome
por: Rodgers, Raymond J, et al.
Publicado: (2019)

Where are the theca cells from: the mechanism of theca cells derivation and differentiation
por: Liu, Tao, et al.
Publicado: (2020)

Wounds of the Spinal Theca
Publicado: (1926)

Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary
por: Imamichi, Yoshitaka, et al.
Publicado: (2017)

Harnessing Expression Data to Identify Novel Candidate Genes in Polycystic Ovary Syndrome
por: Jones, Michelle R., et al.
Publicado: (2011)

Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary
por: Azumah, Rafiatu, et al.
Publicado: (2022)

Identification of novel candidate biomarkers and immune infiltration in polycystic ovary syndrome
por: Na, Zhijing, et al.
Publicado: (2022)

Analysis of Upstream Regulators, Networks, and Pathways Associated With the Expression Patterns of Polycystic Ovary Syndrome Candidate Genes During Fetal Ovary Development
por: Azumah, Rafiatu, et al.
Publicado: (2022)

Discovery of rare ancestry-specific variants in the fetal genome that confer risk of preterm premature rupture of membranes (PPROM) and preterm birth
por: Modi, Bhavi P., et al.
Publicado: (2018)

Tetanus Treated by Injections of Antitoxin into the Spinal Theca
Publicado: (1904)

Case of Hemorrhage into the Ventricles of the Brain, and into the Theca of the Chord
por: Brown, William
Publicado: (1834)

Novel telemetric pressure monitoring in lumbar theca
por: Khawari, Sogha, et al.
Publicado: (2022)

Lipopolysaccharide (LPS) Inhibits Steroid Production in Theca Cells of Bovine Follicles In Vitro: Distinct Effect of LPS on Theca Cell Function in Pre- and Post-selection Follicles
por: MAGATA, Fumie, et al.
Publicado: (2014)

Effect of human ZP3 monoclonal antibody on expression of GDF-9 and number of theca cells in ovary of mice (Mus musculus)
por: Indahwati, Lilik, et al.
Publicado: (2018)

Polycystic Ovary Syndrome
por: Franks, Stephen
Publicado: (1998)

Heterogeneity of Ovarian Theca and Interstitial Gland Cells in Mice
por: Miyabayashi, Kanako, et al.
Publicado: (2015)

Theca lutein cysts and early onset severe preeclampsia
por: Sargin, Mehmet Akif, et al.
Publicado: (2016)

FTO and MC4R Gene Variants Are Associated with Obesity in Polycystic Ovary Syndrome
por: Ewens, Kathryn G., et al.
Publicado: (2011)

Induction of Collagen I by CXCL10 in Ovarian Theca–Stroma Cells via the JNK Pathway
por: Wang, Chaojun, et al.
Publicado: (2022)

Luteinizing hormone stimulates the expression of amphiregulin in human theca cells
por: Liu, Yang, et al.
Publicado: (2022)

Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome
por: Wang, Kexin, et al.
Publicado: (2023)

Pregnancy in polycystic ovary syndrome
por: Kamalanathan, Sadishkumar, et al.
Publicado: (2013)

The inositols and polycystic ovary syndrome
por: Kalra, Bharti, et al.
Publicado: (2016)

On the Therapy for Polycystic Ovary Syndrome
por: Unfer, Vittorio, et al.
Publicado: (2017)

Kisspeptin and Polycystic Ovary Syndrome
por: Tang, Rong, et al.
Publicado: (2019)

Polycystic Ovary Syndrome in Adolescence
por: Deans, Rebecca
Publicado: (2019)

Update on polycystic ovary syndrome
por: Kim, Jin Ju
Publicado: (2021)

Quercetin and polycystic ovary syndrome
por: Ma, Congshun, et al.
Publicado: (2022)

Expression of polycystic ovary syndrome candidate genes in bovine fetal and adult ovarian somatic cells
por: Liu, Menghe, et al.
Publicado: (2022)

ColocQuiaL: a QTL-GWAS colocalization pipeline
por: Chen, Brian Y, et al.
Publicado: (2022)

Metabolomic Insight into Polycystic Ovary Syndrome—An Overview
por: Rajska, Anna, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i8vjh1srneqa1io981i5drqin3