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Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer’s Disease Rats Abrogating Aβ(40/42) and Tau Hyperphosphorylation

Alzheimer’s disease (AD) is the most common form of dementia. Extracellular amyloid-β (Aβ) aggregation and tau hyperphosphorylation are the key drivers of AD. Glycogen synthase kinase 3 (GSK3) and cyclin dependent kinase 5 (Cdk5) have been known as leading applicants arbitrating abnormal tau hyperph...

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Detalles Bibliográficos
Autores principales: Das, Tushar Kanti, Jana, Piyali, Chakrabarti, Swarup Kumar, Abdul Hamid, Mas R.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839535/
https://www.ncbi.nlm.nih.gov/pubmed/31754658
http://dx.doi.org/10.3233/ADR-190135