Synthesis of novel sulfide-based cyclic peptidomimetic analogues to solonamides

Eight new sulfide-based cyclic peptidomimetic analogues of solonamides A and B have been synthesized via solid-phase peptide synthesis and S(N)2’ reaction on a Morita–Baylis–Hillman (MBH) residue introduced at the N-terminal of a tetrapeptide. This last step takes advantage of the electrophilic feat...

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Detalles Bibliográficos
Autores principales: Brango-Vanegas, José, Martinho, Luan A, Bessa, Lucinda J, Vasconcelos, Andreanne G, Plácido, Alexandra, Pereira, Alex L, Leite, José R S A, Machado, Angelo H L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839570/
https://www.ncbi.nlm.nih.gov/pubmed/31728168
http://dx.doi.org/10.3762/bjoc.15.247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839570/
https://www.ncbi.nlm.nih.gov/pubmed/31728168
http://dx.doi.org/10.3762/bjoc.15.247

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