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Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice
BACKGROUND: Sirtuin 1 (SIRT1) is a NAD(+)-dependent enzyme that has important roles in many biological processes involved in aging, including cell growth and repair, inflammation, and energy regulation. SIRT1 activity is modulated in response to certain nutritional interventions that increase health...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599/ https://www.ncbi.nlm.nih.gov/pubmed/31763496 http://dx.doi.org/10.3233/NHA-180059 |