Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice

BACKGROUND: Sirtuin 1 (SIRT1) is a NAD(+)-dependent enzyme that has important roles in many biological processes involved in aging, including cell growth and repair, inflammation, and energy regulation. SIRT1 activity is modulated in response to certain nutritional interventions that increase health...

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Detalles Bibliográficos
Autores principales: Wahl, Devin, Gokarn, Rahul, Mitchell, Sarah J., Solon-Biet, Samantha M., Cogger, Victoria C., Simpson, Stephen J., Le Couteur, David G., de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839599/
https://www.ncbi.nlm.nih.gov/pubmed/31763496
http://dx.doi.org/10.3233/NHA-180059

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