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Feedback-Driven Assembly of the Axon Initial Segment

The axon initial segment (AIS) is a unique neuronal compartment that plays a crucial role in the generation of action potential and neuronal polarity. The assembly of the AIS requires membrane, scaffolding, and cytoskeletal proteins, including Ankyrin-G and TRIM46. How these components cooperate in...

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Detalles Bibliográficos
Autores principales: Fréal, Amélie, Rai, Dipti, Tas, Roderick P., Pan, Xingxiu, Katrukha, Eugene A., van de Willige, Dieudonnée, Stucchi, Riccardo, Aher, Amol, Yang, Chao, Altelaar, A.F. Maarten, Vocking, Karin, Post, Jan Andries, Harterink, Martin, Kapitein, Lukas C., Akhmanova, Anna, Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839619/
https://www.ncbi.nlm.nih.gov/pubmed/31474508
http://dx.doi.org/10.1016/j.neuron.2019.07.029