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Targeted Delivery of siRNA Lipoplexes to Cancer Cells Using Macrophage Transient Horizontal Gene Transfer

Delivery of nucleic acids into solid tumor environments remains a pressing challenge. This study examines the ability of macrophages to horizontally transfer small interfering RNA (siRNA) lipoplexes to cancer cells. Macrophages are a natural candidate for a drug carrier because of their ability to a...

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Detalles Bibliográficos
Autores principales: Wayne, Elizabeth C., Long, Christian, Haney, Matthew J., Batrakova, Elena V., Leisner, Tina M., Parise, Leslie V., Kabanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839649/
https://www.ncbi.nlm.nih.gov/pubmed/31728272
http://dx.doi.org/10.1002/advs.201900582