Metabolic adaptation to glycolysis is a basic defense mechanism of macrophages for Mycobacterium tuberculosis infection

Macrophages are major components of tuberculosis (TB) granulomas and are responsible for host defenses against the intracellular pathogen, Mycobacterium tuberculosis. We herein showed the strong expression of hypoxia-inducible factor-1α (HIF-1α) in TB granulomas and more rapid death of HIF-1α-condit...

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Detalles Bibliográficos
Autores principales: Osada-Oka, Mayuko, Goda, Nobuhito, Saiga, Hiroyuki, Yamamoto, Masahiro, Takeda, Kiyoshi, Ozeki, Yuriko, Yamaguchi, Takehiro, Soga, Tomoyoshi, Tateishi, Yu, Miura, Katsuyuki, Okuzaki, Daisuke, Kobayashi, Kazuo, Matsumoto, Sohkichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839748/
https://www.ncbi.nlm.nih.gov/pubmed/31201418
http://dx.doi.org/10.1093/intimm/dxz048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839748/
https://www.ncbi.nlm.nih.gov/pubmed/31201418
http://dx.doi.org/10.1093/intimm/dxz048

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