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MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia

BACKGROUND AND AIMS: Gastric intestinal metaplasia (IM) is common in the gastric epithelium of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile acids and following chronic inflammation. But the mechanism underlying how bile acids activate CDX2 in gastric ep...

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Detalles Bibliográficos
Autores principales: Li, Ting, Guo, Hanqing, Li, Hong, Jiang, Yanzhi, Zhuang, Kun, Lei, Chao, Wu, Jian, Zhou, Haining, Zhu, Ruixue, Zhao, Xiaodi, Lu, Yuanyuan, Shi, Chongkai, Nie, Yongzhan, Wu, Kaichun, Yuan, Zuyi, Fan, Dai-Ming, Shi, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839796/
https://www.ncbi.nlm.nih.gov/pubmed/30635407
http://dx.doi.org/10.1136/gutjnl-2017-315318