Cargando…
MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia
BACKGROUND AND AIMS: Gastric intestinal metaplasia (IM) is common in the gastric epithelium of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile acids and following chronic inflammation. But the mechanism underlying how bile acids activate CDX2 in gastric ep...
Autores principales: | Li, Ting, Guo, Hanqing, Li, Hong, Jiang, Yanzhi, Zhuang, Kun, Lei, Chao, Wu, Jian, Zhou, Haining, Zhu, Ruixue, Zhao, Xiaodi, Lu, Yuanyuan, Shi, Chongkai, Nie, Yongzhan, Wu, Kaichun, Yuan, Zuyi, Fan, Dai-Ming, Shi, Yongquan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839796/ https://www.ncbi.nlm.nih.gov/pubmed/30635407 http://dx.doi.org/10.1136/gutjnl-2017-315318 |
Ejemplares similares
-
CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype
por: Barros, Rita, et al.
Publicado: (2010) -
Gastric microbes associated with gastric inflammation, atrophy and intestinal metaplasia 1 year after Helicobacter pylori eradication
por: Sung, Joseph J Y, et al.
Publicado: (2020) -
DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia
por: Krishnan, Vaidehi, et al.
Publicado: (2020) -
Chief cell plasticity is the origin of metaplasia following acute injury in the stomach mucosa
por: Caldwell, Brianna, et al.
Publicado: (2022) -
Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP)
por: Lee, Jonathan W J, et al.
Publicado: (2022)