UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal

Elucidation of the molecular cues required to balance adult stem cell self-renewal and differentiation is critical for advancing cellular therapies. Herein, we report that the hematopoietic stem cell (HSC) self-renewal agonist UM171 triggers a balanced pro- and anti-inflammatory/detoxification netwo...

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Detalles Bibliográficos
Autores principales: Chagraoui, Jalila, Lehnertz, Bernhard, Girard, Simon, Spinella, Jean Francois, Fares, Iman, Tomellini, Elisa, Mayotte, Nadine, Corneau, Sophie, MacRae, Tara, Simon, Laura, Sauvageau, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839847/
https://www.ncbi.nlm.nih.gov/pubmed/31703090
http://dx.doi.org/10.1371/journal.pone.0224900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839847/
https://www.ncbi.nlm.nih.gov/pubmed/31703090
http://dx.doi.org/10.1371/journal.pone.0224900

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