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Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening

We investigated a potential use of a 3D tetraculture brain microphysiological system (BMPS) for neurotoxic chemical agent screening. This platform consists of neuronal tissue with extracellular matrix (ECM)-embedded neuroblastoma cells, microglia, and astrocytes, and vascular tissue with dynamic flo...

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Detalles Bibliográficos
Autores principales: Liu, Lumei, Koo, Youngmi, Akwitti, Chukwuma, Russell, Teal, Gay, Elaine, Laskowitz, Daniel T., Yun, Yeoheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839879/
https://www.ncbi.nlm.nih.gov/pubmed/31703066
http://dx.doi.org/10.1371/journal.pone.0224657