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Mechanisms of virus dissemination in bone marrow of HIV-1–infected humanized BLT mice

Immune progenitor cells differentiate in bone marrow (BM) and then migrate to tissues. HIV-1 infects multiple BM cell types, but virus dissemination within BM has been poorly understood. We used light microscopy and electron tomography to elucidate mechanisms of HIV-1 dissemination within BM of HIV-...

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Detalles Bibliográficos
Autores principales: Ladinsky, Mark S, Khamaikawin, Wannisa, Jung, Yujin, Lin, Samantha, Lam, Jennifer, An, Dong Sung, Bjorkman, Pamela J, Kieffer, Collin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839903/
https://www.ncbi.nlm.nih.gov/pubmed/31657719
http://dx.doi.org/10.7554/eLife.46916