Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons

The voltage-gated K(+) channel Kv2.1 serves a major structural role in the soma and proximal dendrites of mammalian brain neurons, tethering the plasma membrane (PM) to endoplasmic reticulum (ER). Although Kv2.1 clustering at neuronal ER-PM junctions (EPJs) is tightly regulated and highly conserved,...

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Detalles Bibliográficos
Autores principales: Vierra, Nicholas C, Kirmiz, Michael, van der List, Deborah, Santana, L Fernando, Trimmer, James S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839919/
https://www.ncbi.nlm.nih.gov/pubmed/31663850
http://dx.doi.org/10.7554/eLife.49953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839919/
https://www.ncbi.nlm.nih.gov/pubmed/31663850
http://dx.doi.org/10.7554/eLife.49953

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