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Identification of a Leukemia-Initiating Stem Cell in Human Mast Cell Leukemia

Mast cell leukemia (MCL) is a highly fatal malignancy characterized by devastating expansion of immature mast cells in various organs. Although considered a stem cell disease, little is known about MCL-propagating neoplastic stem cells. We here describe that leukemic stem cells (LSCs) in MCL reside...

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Detalles Bibliográficos
Autores principales: Eisenwort, Gregor, Sadovnik, Irina, Schwaab, Juliana, Jawhar, Mohamad, Keller, Alexandra, Stefanzl, Gabriele, Berger, Daniela, Blatt, Katharina, Hoermann, Gregor, Bilban, Martin, Willmann, Michael, Winding, Christiana, Sperr, Wolfgang R., Arock, Michel, Rülicke, Thomas, Reiter, Andreas, Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839966/
https://www.ncbi.nlm.nih.gov/pubmed/30953030
http://dx.doi.org/10.1038/s41375-019-0460-6