LOW TRANSLATION DOWNSTREAM OF TOR ACTIVATES MYOGENE EXPRESSION AND ENHANCES HEALTH OF BODY MUSCLE IN C. ELEGANS

Previous studies reported that DR or low nutrient signaling reduces translation and extends lifespan, while attenuating growth and reproduction. In this study using C. elegans as a model organism, we found that reduced translation in neurons or germ tissues increases survival and primes the HSR agai...

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Detalles Bibliográficos
Autores principales: Shim, Juyoung K, Snow, Santina, Howard, Amber, Horrocks, Jordan, Kelley, Joshua, Sayed, Hussein, Rogers, Aric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Session 1520 (Symposium)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6840392/
http://dx.doi.org/10.1093/geroni/igz038.1353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6840392/
http://dx.doi.org/10.1093/geroni/igz038.1353

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