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RESTORATION OF HYPOXIA SIGNALING IMPROVES AGING-ASSOCIATED LOSS OF SKELETAL MUSCLE REGENERATIVE POTENTIAL

Skeletal muscle retains the ability to regenerate throughout life, but this decreases significantly with aging. The present study investigates whether aging-associated loss of muscle hypoxia signaling limits regenerative potential. Utilizing young (3 months) and old (22-24 months) mice, skeletal mus...

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Detalles Bibliográficos
Autores principales: Udeh, Kodi, Li, Bin, Endo, Yori, Panayi, Adriana, Sakthivel, Dharaniya, Neppl, Ron, Wagers, Amy, Sinha, Idranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841091/
http://dx.doi.org/10.1093/geroni/igz038.2679