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Functionalized azetidines via visible light-enabled aza Paternò-Büchi reactions

Azetidines are four-membered nitrogen-containing heterocycles that hold great promise in current medicinal chemistry due to their desirable pharmacokinetic effects. However, a lack of efficient synthetic methods to access functionalized azetidines has hampered their incorporation into pharmaceutical...

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Detalles Bibliográficos
Autores principales: Becker, Marc R., Richardson, Alistair D., Schindler, Corinna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841681/
https://www.ncbi.nlm.nih.gov/pubmed/31704919
http://dx.doi.org/10.1038/s41467-019-13072-x