Upregulation of Yy1 Suppresses Dilated Cardiomyopathy caused by Ttn insufficiency

Truncating variants in TTN (TTNtv), coding for the largest structural protein in the sarcomere, contribute to the largest portion of familial and ambulatory dilated cardiomyopathy (DCM). TTN haploinsufficiency caused by TTNtv is suggested as the disease mechanism. However, it is unclear whether TTN...

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Detalles Bibliográficos
Autores principales: Liao, Dan, Chen, Weiming, Tan, Chia Yee, Wong, Jing Xuan, Chan, Pui Shi, Tan, Lek Wen, Foo, Roger, Jiang, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841687/
https://www.ncbi.nlm.nih.gov/pubmed/31705051
http://dx.doi.org/10.1038/s41598-019-52796-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841687/
https://www.ncbi.nlm.nih.gov/pubmed/31705051
http://dx.doi.org/10.1038/s41598-019-52796-0

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