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Mutation of the PTCH1 gene predicts recurrence of breast cancer

Breast cancer is the most common cancer in women, and some patients develop recurrence after standard therapy. Effective predictors are urgently needed to detect recurrence earlier. The activation of Hedgehog signaling in breast cancer is correlated with poor prognosis. PTCH1 is an essential membran...

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Detalles Bibliográficos
Autores principales: Wang, Chih-Yang, Chang, Yung-Chieh, Kuo, Yao-Lung, Lee, Kuo-Ting, Chen, Pai-Sheng, Cheung, Chun Hei Antonio, Chang, Chih-Peng, Phan, Nam Nhut, Shen, Meng-Ru, Hsu, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841698/
https://www.ncbi.nlm.nih.gov/pubmed/31704974
http://dx.doi.org/10.1038/s41598-019-52617-4