RNF34 overexpression exacerbates neurological deficits and brain injury in a mouse model of intracerebral hemorrhage by potentiating mitochondrial dysfunction-mediated oxidative stress

Intracerebral hemorrhage (ICH) is a common neurological condition associated with high disability and mortality. Alterations in protein ubiquitination have emerged as a key mechanism in the pathogenesis of neurological diseases. Here, we investigated the effects of the E3 ubiquitin ligase ring finge...

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Detalles Bibliográficos
Autores principales: Qu, Xin, Wang, Ning, Chen, Wenjin, Qi, Meng, Xue, Yueqiao, Cheng, Weitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841714/
https://www.ncbi.nlm.nih.gov/pubmed/31704983
http://dx.doi.org/10.1038/s41598-019-52494-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841714/
https://www.ncbi.nlm.nih.gov/pubmed/31704983
http://dx.doi.org/10.1038/s41598-019-52494-x

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