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Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension

Pseudoxanthoma Elasticum (PXE) is a rare disorder characterized by fragmentation and progressive calcification of elastic fibres in connective tissues. Although arterial hypertension (AHT) has been reported in PXE patients, its impact on pathological manifestations has as yet been unexplored. We inv...

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Detalles Bibliográficos
Autores principales: Omarjee, Loukman, Roy, Charlotte, Leboeuf, Christophe, Favre, Julie, Henrion, Daniel, Mahe, Guillaume, Leftheriotis, Georges, Martin, Ludovic, Janin, Anne, Kauffenstein, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841718/
https://www.ncbi.nlm.nih.gov/pubmed/31704980
http://dx.doi.org/10.1038/s41598-019-52808-z