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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases
Mounting evidence suggests that the tumor microenvironment is profoundly immunosuppressive. Thus, mitigating tumor immunosuppression is crucial for inducing sustained antitumor immunity. Whereas previous studies involved intratumoral injection, we report here an inhalable nanoparticle-immunotherapy...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841721/ https://www.ncbi.nlm.nih.gov/pubmed/31704921 http://dx.doi.org/10.1038/s41467-019-13094-5 |