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An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases

Mounting evidence suggests that the tumor microenvironment is profoundly immunosuppressive. Thus, mitigating tumor immunosuppression is crucial for inducing sustained antitumor immunity. Whereas previous studies involved intratumoral injection, we report here an inhalable nanoparticle-immunotherapy...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Crowe, William N., Wang, Lulu, Lu, Yong, Petty, W. Jeffrey, Habib, Amyn A., Zhao, Dawen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841721/
https://www.ncbi.nlm.nih.gov/pubmed/31704921
http://dx.doi.org/10.1038/s41467-019-13094-5