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Tumour Initiation: a Discussion on Evidence for a “Load-Trigger” Mechanism

Appropriate mechanical forces on cells are vital for normal cell behaviour and this review discusses the possibility that tumour initiation depends partly on the disruption of the normal physical architecture of the extracellular matrix (ECM) around a cell. The alterations that occur thence promote...

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Detalles Bibliográficos
Autores principales: Evans, John J., Alkaisi, Maan M., Sykes, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841748/
https://www.ncbi.nlm.nih.gov/pubmed/31598831
http://dx.doi.org/10.1007/s12013-019-00888-z