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Tumour Initiation: a Discussion on Evidence for a “Load-Trigger” Mechanism
Appropriate mechanical forces on cells are vital for normal cell behaviour and this review discusses the possibility that tumour initiation depends partly on the disruption of the normal physical architecture of the extracellular matrix (ECM) around a cell. The alterations that occur thence promote...
Autores principales: | Evans, John J., Alkaisi, Maan M., Sykes, Peter H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841748/ https://www.ncbi.nlm.nih.gov/pubmed/31598831 http://dx.doi.org/10.1007/s12013-019-00888-z |
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