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Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation
The major source of ATP in cancer cells remains unclear. Here, we examined energy metabolism in gastric cancer cells and found increased fatty acid oxidation and increased expression of ALDH3A1. Metabolic analysis showed that lipid peroxidation by reactive oxygen species led to spontaneous productio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841934/ https://www.ncbi.nlm.nih.gov/pubmed/31705020 http://dx.doi.org/10.1038/s41598-019-52814-1 |