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Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation

The major source of ATP in cancer cells remains unclear. Here, we examined energy metabolism in gastric cancer cells and found increased fatty acid oxidation and increased expression of ALDH3A1. Metabolic analysis showed that lipid peroxidation by reactive oxygen species led to spontaneous productio...

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Detalles Bibliográficos
Autores principales:	Lee, Jae-Seon, Kim, Seung Hwa, Lee, Soohyun, Kang, Joon Hee, Lee, Seon-Hyeong, Cheong, Jae-Ho, Kim, Soo-Youl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841934/ https://www.ncbi.nlm.nih.gov/pubmed/31705020 http://dx.doi.org/10.1038/s41598-019-52814-1

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