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A host dTMP-bound structure of T4 phage dCMP hydroxymethylase mutant using an X-ray free electron laser
The hydroxymethylation of cytosine bases plays a vital role in the phage DNA protection system inside the host Escherichia coli. This modification is known to be catalyzed by the dCMP hydroxymethylase from bacteriophage T4 (T4dCH); structural information on the complexes with the substrate, dCMP and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841964/ https://www.ncbi.nlm.nih.gov/pubmed/31705139 http://dx.doi.org/10.1038/s41598-019-52825-y |