Cargando…

Expanding the limits of the second genetic code with ribozymes

The site-specific incorporation of noncanonical monomers into polypeptides through genetic code reprogramming permits synthesis of bio-based products that extend beyond natural limits. To better enable such efforts, flexizymes (transfer RNA (tRNA) synthetase-like ribozymes that recognize synthetic l...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Joongoo, Schwieter, Kenneth E., Watkins, Andrew M., Kim, Do Soon, Yu, Hao, Schwarz, Kevin J., Lim, Jongdoo, Coronado, Jaime, Byrom, Michelle, Anslyn, Eric V., Ellington, Andrew D., Moore, Jeffrey S., Jewett, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841967/
https://www.ncbi.nlm.nih.gov/pubmed/31704912
http://dx.doi.org/10.1038/s41467-019-12916-w