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Expanding the limits of the second genetic code with ribozymes
The site-specific incorporation of noncanonical monomers into polypeptides through genetic code reprogramming permits synthesis of bio-based products that extend beyond natural limits. To better enable such efforts, flexizymes (transfer RNA (tRNA) synthetase-like ribozymes that recognize synthetic l...
Autores principales: | Lee, Joongoo, Schwieter, Kenneth E., Watkins, Andrew M., Kim, Do Soon, Yu, Hao, Schwarz, Kevin J., Lim, Jongdoo, Coronado, Jaime, Byrom, Michelle, Anslyn, Eric V., Ellington, Andrew D., Moore, Jeffrey S., Jewett, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841967/ https://www.ncbi.nlm.nih.gov/pubmed/31704912 http://dx.doi.org/10.1038/s41467-019-12916-w |
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