Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase in CCR5 and CXCR4 chemokines signaling

The role of RhoA GTPases in breast cancer tumorigenesis and metastasis is unclear. Early studies within which mutations in RhoA were designed based on cancer-associated mutations in Ras supported an oncogene role for RhoA. However, recent whole-genome sequencing studies of cancers raised the possibi...

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Detalles Bibliográficos
Autores principales: Kalpana, Gardiyawasam, Figy, Christopher, Yeung, Miranda, Yeung, Kam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841971/
https://www.ncbi.nlm.nih.gov/pubmed/31705019
http://dx.doi.org/10.1038/s41598-019-52746-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841971/
https://www.ncbi.nlm.nih.gov/pubmed/31705019
http://dx.doi.org/10.1038/s41598-019-52746-w

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