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Interplay between integrins and PI4P5K Sktl is crucial for cell polarization and reepithelialisation during Drosophila wound healing

Phosphatidylinositol(4,5)-bisphosphate [PI(4,5)P2] regulates cell adhesion and actin dynamics during cell migration. PI(4,5)P2 binds various components of the cell adhesion machinery, but how these processes affect migration of the epithelial cell sheet is not well understood. Here, we report that P...

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Detalles Bibliográficos
Autores principales: Park, Si-Hyoung, Lee, Chan-wool, Choe, Kwang-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842001/
https://www.ncbi.nlm.nih.gov/pubmed/31704968
http://dx.doi.org/10.1038/s41598-019-52743-z